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KMID : 0606320030190010055
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Journal of Phamacetical Sciences Sookmyung Women s University
2003 Volume.19 No. 1 p.55 ~ p.59
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Effect of Cordyceps pruinosa on the Mice Forced Swimming Test
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Kim Sun-Young
Yang Ki-Sook
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Abstract
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Cordyceps species has been used as antiinflammatory, antitoxics, diuretics in folk remedies. Recent research has been reported the effect of anticancer, antidiabetic, antimutagenic, antilipid perokidation, intestinal immune system modulating activity. Cordyceps pruinosa, which belongs to subgenus Eucordyceps of the Genus Cordyceps, Cordycopidaceae was observed in brown rice and bulled rice supplemented with milk. The activities of Me01f extract and its fraction froln cultivated Cordyceps pruinosa on antifatigue activity induced by the lnice forced swimming test were evaluated. Acute toxicity was investigated. The result revealed that BuOH and H2O fractions showed significant antifatigue effect against immobilized stress. LD50 of each fraction was below 6g/kg.
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